Health
The Menace Of Insulin Resistance
The human body is characterized by a multi
plicity of cells which function to keep it in tact at all times except changes occur due to ailments. Change in the human body is inevitable due to factors ranging from age, lifestyle, and toxins in the environment, diet and knowledge.
The human body in its complexity is yet simple and accurate, precise in healing, regenerating and sustaining. Different climes generally affect and influence the ways the human body function just as neglect has an adverse effect on how it functions.
Most Nigerians live in very poorly ventilated and dirty environment and often attribute environment situations to proper management of landlord or caretakers not taking into cognizance the ailments which accompany such unhealthy environments.
Weight gain and obesity which are common sights in Nigeria are both responsible for countless deaths and untold suffering of many sick persons in Nigeria today.
These cases have been linked as major risk factors for conditions and diseases ranging from insulin resistance to fatty liver disease and the sequelae of non-alcoholic fatty liver disease. Epidemic of the 21st century, obesity is on a steady rise in developing countries with attention focusing on the younger generation.
The World Health Organization has estimated that there are greater than one billion over-weight adults with a body mass index of over 30, and a waistline of more than 88cm or 32 inches in women and 102cm in men and it poses a major public health issues.
Scientists have linked inflammation to obesity which most times precedes diabetes, although one third of hepatitis patients have been known to develop symptoms which can also lead to severe health issues including insulin resistance.
Healthy inclulin is produced to keep inflammation down which reduces a long term risk for diabetes, cancer, osteoporosis but high level insulin generate inflammation which can push calories into fat storage which an impire ovulation and stimulate the ovaries to make too much testosterone, a major cause of polycystic overian syndrome.
Polycystic overian syndrome which is known to lead to various issues which plague women ranging from irregular or absent periods, increased facial hair growth, excessive weight gain and the appearance of multiple small cyst on the overies leading to inability to conceive.
Thus women often miss symptoms like obesity, increased waistline, acanthosis Nigerians or dark velvety appearance of the skin usually around the neck underarms or gain as signs of high insulin levels.
In as much as the situation sounds grave, it is instructive that obese women not only cut down on carbohydrates, but also lose weight as a panacea to regulate insulin levels which can in the long run correct infertility issues or manage diabetes effectively.
Thus, it is instructive, that people take notice of how their body mechanism functions on daily bases, so as to take appropriate medication or consult a physician whenever the need arises.
Tammy Williams is a contributor
Tammy Williams
Two United States scientists who unraveled the human micro RNA have won the Nobel Prize in Physiology or Medicine 2024.
Victor Ambros and Gary Ruvkun won the coveted prize for their work on microRNA as their discoveries help explain how complex life emerged on earth and how the human body is made up of a wide variety of different tissues.
MicroRNAs influence how genes – the instructions for life – are controlled inside organisms, including humans.
Every cell in the human body contains the same raw genetic information, locked in our DNA.
However, despite starting with the identical genetic information, the cells of the human body are wildly different in form and function.
The electrical impulses of nerve cells are distinct from the rhythmic beating of heart cells. The metabolic powerhouse that is a liver cell is distinct to a kidney cell, which filters urea out of the blood.
The light-sensing abilities of cells in the retina are different in skillset to white blood cells that produce antibodies to fight infection.
So much variety can arise from the same starting material because of gene expression.
The US scientists were the first to discover microRNAs and how they exerted control on how genes are expressed differently in different tissues.
The medicine and physiology prize winners are selected by the Nobel Assembly of Sweden’s Karolinska Institute.
They said: “Their groundbreaking discovery revealed a completely new principle of gene regulation that turned out to be essential for multicellular organisms, including humans.
“It is now known that the human genome codes for over 1,000 microRNAs.”
The World Health Organisation (WHO) has begun acting to curb effects of antibiotic pollution.
The new guidance on wastewater and solid waste management for antibiotic manufacturing sheds light on this important but neglected challenge ahead of the United Nations General Assembly (UNGA) High-Level Meeting on antimicrobial resistance (AMR) taking place on 26 September 2024.
The emergence and spread of AMR caused by antibiotic pollution could undermine the effectiveness of antibiotics globally, including the medicines produced at the manufacturing sites responsible for the pollution.
Despite high antibiotic pollution levels being widely documented, the issue is largely unregulated and quality assurance criteria typically do not address environmental emissions. In addition, once distributed, there is a lack of information provided to consumers on how to dispose of antibiotics when they are not used, for example, when they expire or when a course is finished but there is still antibiotic left over.
“Pharmaceutical waste from antibiotic manufacturing can facilitate the emergence of new drug-resistant bacteria, which can spread globally and threaten our health. Controlling pollution from antibiotic production contributes to keeping these life-saving medicines effective for everyone,” said Dr Yukiko Nakatani, WHO Assistant Director-General for AMR ad interim.
Globally, there is a lack of accessible information on the environmental damage caused by manufacturing of medicines.
“The guidance provides an independent and impartial scientific basis for regulators, procurers, inspectors, and industry themselves to include robust antibiotic pollution control in their standards,” said Dr Maria Neira, Director, Department of Environment, Climate Change and Health, WHO. “Critically, the strong focus on transparency will equip buyers, investors and the general public to make decisions that account for manufacturers’ efforts to control antibiotic pollution.”
In a concerted effort to curb brain drain, the Kebbi State Government has harmonised medical doctors’ salaries to be at par with their colleagues in the federal government’s tertiary health facilities.
Kebbi State Commissioner for Health, Musa Inusa-Isma’il, disclosed this at the handing over of ambulances to the state-owned health facilities at the Ministry of Health in Birnin Kebbi yesterday.
Inusa Isma’il, according to a statement by Ahmed Idris, the Chief Press Secretary to the governor, said the essence of the harmonisation was to retain the existing medical doctors and attract more to the services of the state.
According to him, the doctors across the state had already started enjoying the new salaries from August 2024.
He said the release of the vehicles was in fulfilment of Governor Nasir Idris’ promise to uplift health care services in the state.
“His Excellency said I should inform you, the beneficiaries of this gesture, that the vehicle should be strictly used for the intended purpose. It should not be used for anything else.
“If there is no referral case, each of the vehicles must be parked at the hospital by 6 pm. The governor said you should warn your drivers against reckless driving as well as violating the instructions.
“We should also do everything possible to reciprocate the gesture by working according to the terms and conditions attached,” he advised.
The benefiting health facilities included Sir Yahaya Memorial Hospital, Birnin Kebbi; State Teaching Hospital, Kalgo; General Hospital, Argungu; General Hospital, Yauri; General Hospital, Zuru; and General Hospital, Bunza.
In his speech, the permanent secretary of the ministry, Dr Shehu Koko, recalled that the ambulances were handed over to the ministry last Friday by the governor for the onward handover to the benefiting hospitals.
He observed that the ambulances would go a long way in improving the referral system in the state, adding that delays in reaching the secondary and tertiary facilities would be eliminated.
The permanent secretary attributed the high rate of maternal mortality in the country to delays in getting to the health facilities for proper medical care.
“We believe with the provision of these ambulances, part of the gaps we have in our referral system will be addressed, whereby patients who require secondary healthcare could be easily transported to secondary and tertiary health centres, where they can get such help,” he said.
In a goodwill message, Commissioner for Information and Culture Alhaji Yakubu Ahmed expressed gratitude to the governor for the support he has given to the ministry to excel.
While advising the beneficiaries to use the vehicles judiciously, the commissioner advised that services and maintenance of the vehicles must be prompt to derive the maximum benefits from the vehicles.
The commissioner also highlighted some achievements recorded by the government in the last year, including beautification of the state capital, completion of a multimillion-naira ultramodern state secretariat, road construction, construction and renovation of classrooms and upgrading of some health facilities, among others.