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 Olive Oil Boosts Brain Health, Reduces Dementia – Study

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Including olive oil in your regular diet offers several benefits such as protecting heart health or cognitive function.
The Mediterranean staple might also reduce your risk of dying from dementia by 28 per cent if you eat just a spoonful every day.
This new finding is, according to research, presented on Monday in Boston at Nutrition 2023, the annual meeting of the American Society for Nutrition.
Whether olive oil is linked with risk of dementia-related death had never been studied until now, according to the authors.
“Our study reinforces dietary guidelines recommending vegetable oils such as olive oil and suggests that these recommendations not only support heart health but potentially brain health, as well,” said Anne-Julie Tessier, a coauthor of the research and postdoctoral fellow at the Harvard T.H. Chan School of Public Health, in a news release. “Opting for olive oil, a natural product, instead of fats such as margarine and commercial mayonnaise is a safe choice and may reduce the risk of fatal dementia.”
Research participants included nearly 60,600 women who had participated in the Nurses’ Health Study from 1990 to 2018, and nearly 32,000 men who had been in the Health Professionals’ Follow-Up Study during the same time period. The former study investigated risk factors for major chronic diseases among women in North America, whereas the latter is looking into the same topics but for men.
The authors of the latest research assessed the diet of the participants — who were age 56 on average at the start of the study — every four years via a questionnaire. The team also reviewed diet quality using the Alternative Healthy Eating Index, which assigns ratings to foods and nutrients predictive of chronic disease. The higher people score on this index, the better.
Over a follow-up period of 28 years, regardless of diet quality, eating more than half a tablespoon of olive oil per day was associated with a 28 per cent lower risk of dying from dementia, compared with participants who never or rarely consumed olive oil.
Additionally, replacing a daily teaspoon of mayonnaise or margarine with the same amount of olive oil was correlated with an 8 per cent to 14 per cent lower risk of dementia-related death, the authors found.
However, this research is early, so some experts uninvolved with it urge caution.
“These findings are simply being reported at a conference and have not undergone peer-review so there has been no examination of the study by independent experts,” said David Curtis, honorary professor at the UCL Genetics Institute at University College London, in a statement. “We do not know whether the results will end up being published in a journal. If the study does eventually result in a published paper, we do not know whether the published results will be the same as those now being presented.”
People with dementia have 11 times the risk of dying soon after starting any opioids, study finds.
The 4,749 participants who died from dementia were more likely to have APOE e4 — the strongest known genetic risk factor for Alzheimer’s disease — according to analysis of DNA from participants’ blood or mouth cells. But having the gene doesn’t mean a person will certainly develop the disease, and the authors’ findings were still consistent after taking this factor into account, they said.
Regardless, “it is important to note that this is not causal, as the authors point out, only an association,” said registered dietitian Duane Mellor, a senior teaching fellow at Aston Medical School of Aston University in England. “More research is needed.”
Olive oil and dementia risk
The potential benefits of olive oil for brain health could be due to antioxidant compounds that can cross the blood-brain barrier, directly affecting the brain, Tessier said.
“It is also possible that olive oil has an indirect effect on brain health by benefiting cardiovascular health,” she added.

Kevin Nengia

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‘How Micro RNA Research Won Nobel Prize’

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Two United States scientists who unraveled the human micro RNA have won the Nobel Prize in Physiology or Medicine 2024.
Victor Ambros and Gary Ruvkun won the coveted  prize for their work on microRNA as their discoveries help explain how complex life emerged on earth and how the human body is made up of a wide variety of different tissues.
MicroRNAs influence how genes – the instructions for life – are controlled inside organisms, including humans.
Every cell in the human body contains the same raw genetic information, locked in our DNA.
However, despite starting with the identical genetic information, the cells of the human body are wildly different in form and function.
The electrical impulses of nerve cells are distinct from the rhythmic beating of heart cells. The metabolic powerhouse that is a liver cell is distinct to a kidney cell, which filters urea out of the blood.
The light-sensing abilities of cells in the retina are different in skillset to white blood cells that produce antibodies to fight infection.
So much variety can arise from the same starting material because of gene expression.
The US scientists were the first to discover microRNAs and how they exerted control on how genes are expressed differently in different tissues.
The medicine and physiology prize winners are selected by the Nobel Assembly of Sweden’s Karolinska Institute.
They said: “Their groundbreaking discovery revealed a completely new principle of gene regulation that turned out to be essential for multicellular organisms, including humans.
“It is now known that the human genome codes for over 1,000 microRNAs.”

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WHO Begins Regulation On Antibiotic Waste

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The World Health Organisation (WHO) has begun acting to curb effects of antibiotic pollution.
The new guidance on wastewater and solid waste management for antibiotic manufacturing sheds light on this important but neglected challenge ahead of the United Nations General Assembly (UNGA) High-Level Meeting on antimicrobial resistance (AMR) taking place on 26 September 2024.
The emergence and spread of AMR caused by antibiotic pollution could undermine the effectiveness of antibiotics globally, including the medicines produced at the manufacturing sites responsible for the pollution.
Despite high antibiotic pollution levels being widely documented, the issue is largely unregulated and quality assurance criteria typically do not address environmental emissions. In addition, once distributed, there is a lack of information provided to consumers on how to dispose of antibiotics when they are not used, for example, when they expire or when a course is finished but there is still antibiotic left over.
“Pharmaceutical waste from antibiotic manufacturing can facilitate the emergence of new drug-resistant bacteria, which can spread globally and threaten our health. Controlling pollution from antibiotic production contributes to keeping these life-saving medicines effective for everyone,” said Dr Yukiko Nakatani, WHO Assistant Director-General for AMR ad interim.
Globally, there is a lack of accessible information on the environmental damage caused by manufacturing of medicines.

 

“The guidance provides an independent and impartial scientific basis for regulators, procurers, inspectors, and industry themselves to include robust antibiotic pollution control in their standards,” said Dr Maria Neira, Director, Department of Environment, Climate Change and Health, WHO. “Critically, the strong focus on transparency will equip buyers, investors and the general public to make decisions that account for manufacturers’ efforts to control antibiotic pollution.”

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Kebbi Harmonises Doctors’ Salaries To Curb Brain Drain

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In a concerted effort to curb brain drain, the Kebbi State Government has harmonised medical doctors’ salaries to be at par with their colleagues in the federal government’s tertiary health facilities.
Kebbi State Commissioner for Health, Musa Inusa-Isma’il, disclosed this at the handing over of ambulances to the state-owned health facilities at the Ministry of Health in Birnin Kebbi yesterday.
Inusa Isma’il, according to a statement by Ahmed Idris, the Chief Press Secretary to the governor, said the essence of the harmonisation was to retain the existing medical doctors and attract more to the services of the state.
According to him, the doctors across the state had already started enjoying the new salaries from August 2024.
He said the release of the vehicles was in fulfilment of Governor Nasir Idris’ promise to uplift health care services in the state.
“His Excellency said I should inform you, the beneficiaries of this gesture, that the vehicle should be strictly used for the intended purpose. It should not be used for anything else.
“If there is no referral case, each of the vehicles must be parked at the hospital by 6 pm. The governor said you should warn your drivers against reckless driving as well as violating the instructions.
“We should also do everything possible to reciprocate the gesture by working according to the terms and conditions attached,” he advised.
The benefiting health facilities included Sir Yahaya Memorial Hospital, Birnin Kebbi; State Teaching Hospital, Kalgo; General Hospital, Argungu; General Hospital, Yauri; General Hospital, Zuru; and General Hospital, Bunza.

 

 

In his speech, the permanent secretary of the ministry, Dr Shehu Koko, recalled that the ambulances were handed over to the ministry last Friday by the governor for the onward handover to the benefiting hospitals.
He observed that the ambulances would go a long way in improving the referral system in the state, adding that delays in reaching the secondary and tertiary facilities would be eliminated.
The permanent secretary attributed the high rate of maternal mortality in the country to delays in getting to the health facilities for proper medical care.
“We believe with the provision of these ambulances, part of the gaps we have in our referral system will be addressed, whereby patients who require secondary healthcare could be easily transported to secondary and tertiary health centres, where they can get such help,” he said.
In a goodwill message, Commissioner for Information and Culture Alhaji Yakubu Ahmed expressed gratitude to the governor for the support he has given to the ministry to excel.
While advising the beneficiaries to use the vehicles judiciously, the commissioner advised that services and maintenance of the vehicles must be prompt to derive the maximum benefits from the vehicles.
The commissioner also highlighted some achievements recorded by the government in the last year, including beautification of the state capital, completion of a multimillion-naira ultramodern state secretariat, road construction, construction and renovation of classrooms and upgrading of some health facilities, among others.

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